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Core Technology

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C&C Core Technology
  Core Technology New Strategy of Drug Discovery
Medicinal chemistry
  • Hit to Lead / Lead to Clinical Candidate
    • - Focused/Druggable Chemical Library for H/I
    • - High Quality of LBDD for L/I to L/O
    • - Early Process Chemistry for preclinical study
  • Through-put System
    • - Auto purification-analyses
      (HPLC, LC-MS, GC, prepLCs etc.)
    • - Synthetic Equipment's (M/W, Microsynth. etc.)
Proof of Mechanism & Principle
CADD / Bioinformatics
  • SBDD/Homology modeling
  • In silico Screening
    • - Prediction of Selectivity (kinases/transporters)
    • - Prediction of ADMET
    • - Prediction of CYPs
  • Genome based Analyses
    • - DEG, GSEA, Signal pathway map etc.
Pharmacology / Molecular
biology
  • Direct binding (FP, SPR)
  • Transient/Stable Reporter gene assay
  • Cell viability assay (2D, 3D)
  • Transient/Stable K/D systems
  • Ex-vivo assay
  • DMPK/PK-PD
  • Xenograft models (sc, orthotopic)
  • Inflammation models (acute, chronic)