| 1 |
The therapeutic efficacy of the novel uricosuric agent UR-1102 for hyperuricemia and gout.
EULAR (The European League Against Rheumatism) Congress, 2013
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| 2 |
Discovery of Tofogliflozin, a Novel C-Arylglucoside with an O-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes.
J Med Chem, 2012, 55, 7828
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| 3 |
9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors.
J Med Chem, 2011, 54, 6286
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| 4 |
Newly discovered orally active pure antiestrogens.
Bioorganic & Medicinal Chemistry Letters , 16, 4959-4964, 2006.
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| 5 |
Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens.
Bioorganic & Medicinal Chemistry Letters , 16, 4090-4094, 2006.
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| 6 |
Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure-activity relationship.
Bioorganic & Medicinal Chemistry, 14, 4803-4819, 2006.
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| 7 |
Role of aspartate 351 in transactivation and active conformation of estrogen receptor α.
J. of Mol. Endocrinol., 35, 449-464, 2005.
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| 8 |
Rapid Screening of Drug Absorption Potential Using Immobilized Artificial Membrane Phosphatidylcholine Column and Molar Volume.
Chromatographia, 60, 399-404, 2004.
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| 9 |
Evaluation of KCB-328, a new Ikr blocking antiarrhythmic agent in pacing induced canine arterial fibrillation.
Europace, 6, 384-391, 2004
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| 10 |
Differential Recovery of Action Potential Duration and HERG Currents from the Effects of Two Methanesulfonamide Class Ⅲ Antiarrhythmic Agents, KCB-328 and Dofetilide,
Journal of Cardiovascular Pharmacology, 42(5), 648-655, 2003.
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| 11 |
Ikr Channel Blockers: Novel Antiarrhythmic Agents.
Curr. Med. Chem.-Cardiovascular & Hematological Agents, 1(3), 203-223, 2003.
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| 12 |
The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis.
Thrombosis and Haemostasis, 86(6), 1512-1520, 2001.
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| 13 |
Electrophysiologic and antiarrhythmic effects of the new class III antiarrhythmic drug KCB-328 in experimental canine atrial flutter.
J. Cardiovasc Pharmacol Ther., 6(3), 297-306, 2001
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| 14 |
In Vitro and In Vivo Studies of AT-1362, A Newly Synthesized and Orally Active Inhibitor of Thrombin.
Thrombosis Research, 100(1), 97-107, 2000.
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| 15 |
Clofilium, a potassium channel blocker, induces apoptosis of human promyelocyte leukemia(HL-60) cells via Bcl-2-insensitive activation of caspase-3.
Cancer Letters, 147(1-2), 85-93, 1999.
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| 16 |
Synthesis and Biological Activity of KCB-328 and its Analogues: Novel Class III Antiarrhythmic Agents with Little Reverse Frequency Dependence.
Bioorganic & Medicinal Chemistry Letters, 9:85-90, 1999.
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| 17 |
Studies on the New Factor on the Regulation of Contraction in the Balloon Injured Rabbit Carotid Artery.
Kor. J. Gerontol, 8(1), 67-76, 1998.
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| 18 |
KCB-328: A Novel Class III Antiarrhythmic Agent with Little Reverse Frequency Dependence in Isolated Guinea-Pig Myocardium.
Journal of Cardiovascular Pharmacology, 31(4), 609-617, 1998.
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| 19 |
Cloning and Nucleotide Sequence of the DNA Gyrase gyrA Gene from Serratia marcescens and Characterization of Mutations in gyrA of Quinolone-Resistant Clinical Isolates.
Antimicrobial Agents and Chemotherapy, 42(1), 190-193, 1998.
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| 20 |
Effects of a new class III antiarrhythmic drug, KCB-328 on canine arrhythmic models.
The Japanese Journal of Pharmacology, 71(suppl I), 138, 1996.
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| 21 |
Electrophysiological effects of KCB-328. A novel Class III antiarrhythmic agent in vitro.
The FASEB Journal, 10(3), A32, 1996.
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| 22 |
Frequency-dependent effects of KCB-328. A novel Class III antiarrhythmic agent in isolated guinea pig ventricular muscle.
The FASEB Journal, 10(3), A32, 1996.
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| 23 |
Role of aspartate 351 in transactivation and active conformation of estrogen receptor α.
J. of Mol. Endocrinol., 35, 449-464, 2015.
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| 24 |
Discovery of a Novel Highly Selective Histamine H4 Receptor Antagonist for the Treatment of Atopic Dermatitis.
J Med Chemm, 2018, 61(7), 2949
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